Possible Interactions with: Bromelain
If you are currently being treated with any of the following medications, you should not use bromelain without talking to your health care provider.
Antibiotics -- Bromelain may increase the amount of antibiotics absorbed by the body. In one clinical study, the combination of bromelain and amoxicillin increased the levels of amoxicillin in the blood. Also, some studies suggest that bromelain may increase the body's absorption of tetracycline, but results of other studies have been conflicting.
Anticoagulants and antiplatelet drugs (blood-thinners) -- Bromelain may affect the blood's ability to clot, and could interfere with any blood-thinning drugs you are taking, including:
- Warfarin (Coumadin)
- Clopidogrel (Plavix)
Sedatives -- Some experts believe bromelain may increase the effect of drugs that have a sedating effect, including:
- Anticonvulsants such as phenytoin (Dilantin) and valproic acid (Depakote)
- Benzodiazepines such as alprazolam (Xanax) and diazepam (Valium)
- Drugs to treat insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), and ramelteon (Rozerem)
- Tricyclic antidepressants such as amitriptyline (Elavil)
The same is true of herbs with a sedating effect, such as valerian, kava, and catnip.
- Last reviewed on 6/15/2007
- Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.