Azilsartan/chlorthalidone (By mouth)
Azilsartan Medoxomil (ay-zil-SAR-tan me-DOX-oh-mil), Chlorthalidone (klor-THAL-i-done)
Treats high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. This medicine contains an angiotensin II receptor blocker (ARB) and a diuretic (water pill).
When This Medicine Should Not Be Used
How to Use This Medicine
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Carefully follow your doctor's instructions about any special diet.Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
If a dose is missed:
- Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Protect the medicine from light and moisture. Keep your medicine in the original container until you are ready to use it.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using aliskiren (Tekturna®), digoxin (Lanoxin®), lithium (Eskalith®, Lithobid®), a diuretic (water pill, such as furosemide, hydrochlorothiazide, torsemide, Demadex®, Lasix®), or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
- Do not use this medicine together with aliskiren (Tekturna®) if you have diabetes.
- Make sure your doctor knows if you follow a low-salt diet.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Make sure your doctor knows if you are breastfeeding, or if you have kidney problems, liver disease, congestive heart failure, gout, or low potassium or sodium in your blood.
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated.
- Tell your doctor right away if you dry mouth, increased thirst, muscle cramps, nausea, or vomiting. These could be symptoms of low potassium levels.
- Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Change in how much or how often you urinate
- Confusion, weakness in your hands and feet, uneven heartbeat, trouble breathing
- Dry mouth, increased thirst, muscle cramps, nausea or vomiting
- Joint pain or swelling
- Lightheadedness, dizziness, fainting
If you notice these less serious side effects, talk with your doctor:
- Unusual tiredness or weakness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 4/4/2014
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